Lately Strega Nona has been distracted-she even gave Signore Mayor the wrong remedy for his headache. One night Nona has a dream about her Grandma Concetta, who has been in heaven for many years, and her little house at the seashore. Nona decides that she will take a vacation there. While Strega Nona is away, Bambolona will do the daily remedies and Big Anthony will do the chores. With these two left in charge, what could possibly go wrong?