The revised, updated, and expanded second edition of this book reflects the most recent advances in the diagnosis and treatment of childhood brain tumours. Major sections of the book focus on principles of diagnosis and treatment, specific brain tumours, and complications of therapy. All chapters have been updated to provide current information on topics such as noninvasive imaging; haematopoietic growth factors; new techniques in radiation, surgery, and chemotherapy; radiation-induced neurotoxicity in long-term survivors; and new molecular biologic techniques that will affect treatment in the future. New chapters on neuropathology and biologic response modifiers have also been added. The chapter on neuropathology includes discussions of immunohistochemistry, monoclonals, and other tumour markers. The chapter on biologic response modifiers discusses monoclonal antibodies, cytogenetic advances, oncogenes and anti-oncogenes, and immune modulation.