The Johns Hopkins White Papers are a series of in-depth special reports written by some of the nation's leading doctors, all specialists in their respective fields. Each White Paper summarizes the very latest research and findings from all of the major medical journals, in easy to use language for the lay person to understand. We currently have thirteen different titles. There has been a recent surge in arthritis research, coupled with an increase in available treatments, such as COX-2 inhibitors for osteoarthritis and new disease-modifying anti-rheumatic drugs. We review the most up-to-date information on the causes, prevention, and treatment of arthritis and related conditions.