This is the Eighth Edition of the comprehensive and well-respected text and reference of pathophysiology. As a nurse-physiologist, Carol Porth uniquely emphasizes "concepts" of altered health states, as opposed to factual descriptions of diseases and disorders. This conceptual model integrates the developmental and preventative aspects of health. By taking this physiologic approach, the author ensures a comprehension of the whole of body function. By integrating all of the aspects of the human body into a total functional whole, the student can grasp both the physical and psychological aspects of altered health.This edition has a completely revamped art program and new displays that showcase pathophysiological processes though detailed visual representation. Other highlights include a greater international focus, expanded content on evidence-based practice and completely revised, updated chapters on genetics, disorders of white blood cells and lymphoid tissues, and innate and acquired immunity.A bound-in CD-ROM and companion Website include Weblinks, an NCLEX® tutorial, a Spanish-English audio glossary, monographs of 100 most commonly prescribed drugs, over 30 Concepts in Action animations, 5 Clinical Simulations, and dosage calculation quizzes. An Instructor's Resource DVD-ROM and online instructor resources are also available.