The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism (Proteins and Cell Regulation)
- ISBN 10: 1402065604
- ISBN 13: 9781402065606
- Edition: 1
- Release: 2007-12-04
- Format: Hardcover (328 pages)
- List Price: $169.00
- Tags: Medicine, General, Basic Science, Biochemistry, General AAS, Internal Medicine
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Book Description: Research into the paraoxonase (PON) multigene family has really only blossomed in the last 10 years. Before this time only PON1 was known and research was restricted to toxicologists investigating the metabolism of organophosphate insecticides and nerve gases and a few "mad" scientists searching for "natural" substrates. Since this time two new members PON2 and PON3 have been discovered, all 3 PONs have been shown to act as antioxidants and the PON family has taken centre stage as major players in the development of a wide variety of diseases such as cardiovascular disease, diabetes mellitus, rheumatism, Alzheimers and many more while remaining important in determining organophosphate toxicity.In September 2006 the 2nd International Conference on Paraoxonases took place in Hajduszoboszlo, Hungary, bringing together the worlds foremost experts in the field. The current book is a distillation of the plenary lectures which took place at the meeting, resulting in a comprehensive up-to-date, state-of-the-art review of current paraoxonase research.
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