This text is not a basic introduction, so it assumes some degree of knowledge about Alzheimer's Disease (AD) on the part of the reader. By setting our discussion at this level, it allows us to keep readers informed of evidence-based developments in the field. We think that our text will always have a comprehensive and current bibliography for individuals who are newly entering the field of AD studies, either as clinicians, researchers, or individuals with industrial interests, as well as seasoned investigators. Although we focus on evidence-based approaches rather than on opinions, we hope that our book is useful to informed members of the public as well as to doctors and scientists. We want to balance optimism and hopefulness against the very significant challenges of understanding and treating this illness. The fact that individuals can obtain access to the online book, or purchase a single chapter or a full textbook, should add to the versatility and reflects our desire to meet individual needs.