This laboratory manual is designed for an introductory majors biology course with a broad survey of basic laboratory techniques. The experiments and procedures are simple, safe, easy to perform, and especially appropriate for large classes. Few experiments require a second class-meeting to complete the procedure. Each exercise includes many photographs, traditional topics, and experiments that help students learn about life. Procedures within each exercise are numerous and discrete so that an exercise can be tailored to the needs of the students, the style of the instructor, and the facilities available.